all informations about alzental

Composition Suspension (1ml) 1 Tablet Albendazole 20 mg 200 mg Properties and Mode of Action ALZENTAL a benzimidazole carbamate derivative, is an anthelmintic with activity against most nematode and some other worms. Activity against some larval stages and ova has also been demonstrated. ALZENTAL’s anthelmintic activity is considered to be dependent on the inhibition or destruction of cytoplasmic microtubules in the worm’s intestinal or absorptive cells. Inhibition of glucose uptake and depletion of glycogen stores follow as do other inhibitory effects Ieading to death of the worm. Indications ALZENTAL is a broad spectrum anthelmintic used in the treatmemt of single and mixed infections as: Enterobiasis Ascariasis Hookworms Trichuriasis Strongyloidiasis Taeniasis Capillariasis Cysticercosis Toxocariasis Trichostrongyliasis Trichinosis Echinococcosis (Hydatid disease) Dosage and Administration Adults and Children Above 2 years of age: Enterobiasis, Ascariasis, Hookworm, Trichuriasis: 400 mg as a single dose. Treatment may be repeated in 3 weeks. Cysticercosis: 15 mg/kg body weight/day for 30 days. Strongyloidiasis and Taeniasis: 400 mg is given daily for 3 consecutive days. This may be repeated after 3 weeks if necessary. Capillariasis: 200 mg twice daily for 10 days. Echinococcosis (Hydatid disease): (Over 60 kg body weight): 800 mg/day in divided doses for 28 days. This is followed by 2 weeks drug free interval, to be repeated for 2-3 cycles. For inoperable cases up to 5 cycles may be given. (Under 60 kg body weight): 10-15 mg/kg body weight daily for 28 days. Children Up to 2 years of age: Enterobiasis, Ascariasis, Hookworm, Trichuriasis: 200 mg as a single dose. Treatment may be repeated in 3 weeks. Precautions ALZENTAL may cause elevation in hepatic enzymes. Patients receiving high doses of ALZENTAL such as those with Hydatid disease, should be supervised closely with blood counts and liver function being monitored. Contra_indications Pregnancy. Hypersensitivity to Albendazole. Side effects Incidence is rare and reversible: e.g.nausea, vomiting, diarrhoea, leucopenia, elevated transaminases. Presentation ALZENTAL Suspension :Bottle of 20 ml. ALZENTAL Tablets : Box of 1 blister of 2 tablets.