all informations about levoxin eye drops

Composition: Each ml contains 5mg Levofloxacin (as hemihydrate)

Antibacterial Activity:
- Levoxin® Eye Drops 0.5% is a sterile topical ophthalmic solution. Levofloxacin is the L-isomer of the racemic mixture Ofloxacin which has potent antibacterial activity. Unlike Ofloxacin or Ciprofloxacin, Levoxin® Eye Drops exhibits bactericidal effect against Gram +ve bacteria, in addition to Gram –ve and atypical pathogens.
- Levoxin® Eye Drops, which belongs to Fluoroquinolone structure and is active against bacteria resistant to aminoglycosides. The mechanism of action of Levofloxacin involves the inhibition of bacterial topoisomerases IV and DNA gyrase
- The antibacterial spectrum of Levoxin® Eye Drops include:

Aerobic Gram Positive Bacteria
- Different species of staphylococci e.g.:
• Staph. aureus (including penicillinase producer)
• Staph. epidermidis
• Staph. saprophyticus

- Different species of streptococci e.g.:
• S. pneumoniae (including penicillin resistant species)
• S. pyogenes
• S. viridans
• S. faecalis

Other Gram positive bacteria e.g.
- Listeria monocytogenes
- Mycobacterium tuberculosis

Aerobic Gram negative bacteria
- Haemophilus influenzae
- Morganella morganii
- Legionella pneumophilla
- Providencia spp.
- Klebsiella pneumoniae
- Salmonella spp.
- Escherichia coli
- Proteus mirabilis
- Moraxella catarrhalis
- Shigella spp.
- Neisseria gonorrhea
- Yersinia spp.
- Pseudomonas aeruginosa
- Enterobacter spp.
- Atypical bacteria
- Anaerobic bacteria
- Chlamydia trachomatis
- Bacteroides fragilis
- Chlamydia pneumoniae
- Clostridium perfringens
- Mycoplasma pneumoniae

Properties: Pharmacological Properties:
Levoxin® 0.5% topical ophthalmic solution has excellent penetration into the plasma and tears and its concentration exceeds the minimum inhibitory concentration for different ocular pathogens.

Indications: Levoxin® 0.5% eye drops is indicated mainly for the treatment of bacterial conjunctivitis and other different bacterial infections.
Contra-Indictions: Levoxin® Eye Drops 0.5% is contraindicated in patients with a history of hypersensitivity to Levofloxacin or any of its components.
Levoxin® Eye Drops 0.5% is not for ocular injection.

Dosage & Administration: For adults and children above 1year 
Instill one to two drops in the affected eye every 2 hours while awake, up to 8 times per day, and then reduce frequently as infection is controlled.


How supplied: Levoxin® Eye Drops 0.5% is supplied in a bottle with a controlled dropper tip containing 5ml isotonic solution of Levofloxacin 5mg/ml.

Also available:
Levoxin® Tablets: Each Tablet contains Levofloxacin 500 or 250mg in packs of one strip of 5 tablets.
Levoxin® Vials: Each Vial contains Levofloxacin 500mg in packs of 100ml bottle for slow intravenous administration (at least one hour)